Missouri has established itself as the premier success story for cannabis in the Midwest, evolving from a standard medical regime to a high-volume adult-use market that exceeded $1.52 billion in annual sales in 2025. As the market enters the 2026–2027 biennium, the landscape is shifting from rapid expansion toward operational maturation and specialized entry.
North Carolina remains one of the final significant jurisdictions in the United States without a comprehensive medical or adult-use cannabis program. However, the 2026–2027 biennium is projected to be the most consequential period in the state’s cannabis history. Driven by the formation of the North Carolina Advisory Council on Cannabis and an impending federal “hemp cliff,” the state is moving from a period of passive prohibition toward a structured, albeit highly restrictive, regulatory framework.
Nebraska is entering the 2026–2027 biennium at a historic crossroads. Following the 71% voter approval of Initiatives 437 and 438 in late 2024—the largest margin for a medical cannabis initiative in U.S. history—the state is currently standing up its first regulated medical infrastructure.
Florida represents the most capital-intensive and professionally structured cannabis market in the nation. As of 2026, the state is at a crossroads: it is both expanding its mature medical program and preparing for a potential constitutional shift toward universal adult-use access. On November 3, 2026, Florida voters will decide on the Marijuana Legalization Initiative (Amendment 3). Passing this requires a 60% supermajority—a high threshold, but one that polls suggest is within reach.
As Virginia transitions from its current “possession-only” model toward a fully regulated retail market, the 2026–2027 biennium represents a once-in-a-generation window for market entry. Unlike the vertically integrated “medical-only” regimes of the past, Virginia’s upcoming framework focuses on decentralization, specifically architected to favor small Virginia-based operators over large multi-state corporations.
Minnesota is currently undergoing a transformative shift in its cannabis landscape, moving from a semi-regulated hemp-derived market toward a fully comprehensive adult-use framework. Overseen by the Office of Cannabis Management (OCM), the 2026–2027 biennium represents the critical “enforcement phase” where temporary registrations sunset and permanent, merit-based licenses define the market’s long-term leaders.
The cannabis industry is experiencing rapid growth, projected to expand from nearly $33 billion in 2023 to $49 billion by 2026. While legalization has provided economic opportunities in many states, Native American tribes face significant hurdles in accessing this booming market due to federal and state regulatory barriers. Tribes seeking entry into the cannabis industry encounter unique challenges, including difficulties in securing licensing, financing, and banking services—all essential components for launching and sustaining a cannabis business.
A recent California Superior Court ruling has sent ripples through the cannabis industry by allowing a class-action lawsuit to proceed against Valley Crest Farms, a greenhouse cannabis cultivation operation in Carpinteria Valley. The case revolves around persistent odor complaints from nearby residents, who claim that the strong, unpleasant smell of cannabis has negatively impacted their property values, businesses, and overall quality of life.
Everyone deserves a second chance, and for many Minnesotans, clearing an old criminal record can be the key to unlocking new opportunities. The Minnesota Attorney General’s Office is dedicated to helping individuals move forward with a clean slate by hosting Clean Slate Expungement Clinics across the state. These clinics provide an opportunity for eligible individuals to have their state court records sealed—removing barriers to employment, housing, and professional licensing.
